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KMID : 0604520190450010077
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Journal of the Society of Cosmetic Scientists of Korea
2019 Volume.45 No. 1 p.77 ~ p.85
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Physiological Activity of Coptis japonica, White Poria cocos, and Cimicifuga heracleifolia and a Mixture of Their Extracts on Skin Based on The Oriental Medicine OMiYakSung Theory
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Ryu Hwa-Sun
Oh Seong-Hwa
Lee Jung-No
Kim Hee-Taek
Ha Hun-Yong
Kim Yong-Min
Park Sung-Min
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Abstract
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OMiYakSung theory consists of various herbs that contain at least one or more of the five flavors. This theory has been used to prevent human diseases and enhance the immune system. The main objective of the present study was to investigate efficacy differences and changes in ingredients of blended and single herb extracts based on OMiYakSung theory. We selected three herbs Coptis japonica Makino, Cimicifuga heracleifolia Komarov, and white Poria cocos and assessed their physiological effect. As results, the blended extracts showed excellent cell migration effect at 400 ug/mL concentration, compared to the single extract. In addition, the blended extracts enhanced immune function by increasing the activity of dendritic cells and showed the highest antioxidant activity by DPPH assay and HPLC-ABTS assay. In this study, we developed a new materials that can be applicable to cosmetics and pharmaceuticals field by applying oriental medicine theory.
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KEYWORD
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OMiYakSung, five flavor, blended extract, ferulic acid
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